Personally, I think it's stupid when a western creator, for example, uses right to left like as if it's a style just to make it look cool and very Japanese like, it irritates me even more if they use Japanese sound effects >.>
My series is heavily inspired off of manga and is read left to right, I've had quite a few people tell me that
"But what if it got a Japanese translation and what if Japanese readers didn't like having to read it the other way?"
My answer to that is well tough shit? We had to get used to reading right to left, so I see no reason why they can't get used to reading left to right.
If a creator feels more comfortable drawing their comic that way then by all means, go for it. Even though it annoys me sometimes it won't turn me away if I find the story and art intriguing.